Sodium Nitrate And Brain Tumors

Hot dogs are on almost every child’s list of favorite foods. Second ranking would probably be bologna and pepperoni sausage. Many kids also eat deli lunch meats on a fairly regular basis.

But could these American staple foods be killing our children? In 1995, a petition was brought before the commissioner of the Food and Drug Administration (FDA) requesting the FDA to require a cancer risk warning on packages of hot dogs that contain preservatives called nitrites. The grounds for this petition were alarming: scientific information on excess risks of childhood brain tumors and leukemia have been linked to the consumption of hot dogs-specifically hot dogs containing nitrite preservatives.

Why do food manufacturers use these additives in deli meats? Nitrites, specifically Sodium Nitrite or Potassium Nitrite, are used to prevent botulism as well as improve the color and flavor of the meat.

Nearly all processed meats are made with sodium nitrite: breakfast sausage, hot dogs, jerkies, bacon, lunch meat, and even meats in canned soup products. During the cooking process, nitrites combine with amines naturally present in the meat to form cancer-forming compounds called nitrosamines or N-nitroso. When consumers eat these nitrosamines, they promote the growth of various cancers in the body, including colorectal cancer, pancreatic cancer, and cancer of the oral cavity, urinary bladder, esophagus, stomach and brain.

Plenty of evidence points to risks to cancer in children from eating foods containing nitrities. In 1982, a study found that pregnant women who ate meats treated with sodium nitrite had a higher chance of brain tumors developing in their children.

Recent case-control studies have confirmed the risks of cancer from consumption of hot dogs. Eating many hot dogs by children, as well maternal hot dog consumption during pregnancy, has been shown to be associated with brain cancer and leukemia in children.

Another study was performed between 1986 and 1989 on children who were diagnosed with brain cancer before age six. Of 53 foods and beverages and three alcoholic beverages consumed by mothers during pregnancy, only hot dogs were associated with an excess risk of childhood brain tumor.

A study in Denver of 234 children with cancer found another strong connection between brain tumors and hot dog consumption. Mothers who ate hot dogs one or more times a week during pregnancy had about twice the risk of brain tumors developing in their children. Children who ate hot dogs at least once a week were also at higher risk of the disease. Perhaps the most interesting fact in this study is children who ate hot dogs and didn’t take vitamins (which retard the development of N-nitroso carcinogens) were more linked to acute lymphocytic leukemia and brain tumors. The study concluded with:

“The results linking hot dogs and brain tumors (replicating an earlier study) and the apparent synergism between no vitamins and meat consumption suggest a possible adverse effect of dietary nitrites and nitrosamines.”

A study in Los Angeles area in the 1980’s looked at the connection between eating certain foods and the development of leukemia in children before the age of 10. Children who consumed a dozen or more hot dogs a month had nearly nine times the regular risk of contracting childhood leukemia. They also found a connection between fathers who ate a dozen hot dogs a month and their children developing childhood leukemia.

The harmful effects of nitrites affect more than children. A study in Sweden discovered that Swedes who consumed about 3 ounces of processed meat daily had a 15% higher risk of contracting stomach cancer compared to those that ate 2 or less ounces.

A report in the Journal of the National Cancer Institute studied 190,000 people of age between 45 and 75 across seven years. Conducted by the Cancer Research Center of Hawaii and the University of Southern California, the study concluded that those who ate the most bacon, ham, or cold cuts (processed meats) had a 68% higher risk of developing pancreatic cancer compared to those who ate the least.

Per 1,000 calories consumed, “most” was determined as consuming a minimum of 1-ounce beef, 0.3-ounce pork, or 0.6 ounce of processed meat.

The meat processing industry likes using sodium nitrite to make meats look more appetizing. In the 1970’s, the USDA tried to ban the additive but failed. The meat industry said that despite the risks, sodium nitrite helped contain the growth of bacteria that causes botulism.

However, there are safer methods of slowing the growth of botulism – they just do not improve the coloring of the meat. Botulism spores germinate more slowly with refrigeration, but the meat manufacturers say consumers may not be as careful with refrigeration as they should, causing needless deaths. Cooking the meat properly also keeps the problem in check. And it takes some time for botulism to form in food. Dr. Ross Hume Hall conducted an experiment of leaving bacon at 80 degrees Fahrenheit and discovered it took 10 days for the spored to reach toxic levels (or much better if it was refrigerated). Hall stated that throw-away dates on meats is something consumers could adopt easily.

I don’t know about you, but I would rather have an earlier expiration date, especially if it would mean putting an end to sodium nitrite in our food.

Expectant mothers should avoid consuming meats that contain sodium nitrite due to the greatly heightened risk of brain tumors in infants. Parents should also be warned to avoid feeding their children products that contain sodium nitrite, including all popular hot dogs, bacon, jerkies, breakfast sausages and pizzas made with pepperoni or other processed meats. Sodium nitrite is especially dangerous to fetuses, infants and children.

Sadly, nearly all school lunch programs currently serve schoolchildren meat products containing sodium nitrite. Hospital cafeterias also serve this cancer-causing ingredient to patients. Sodium nitrite is found in literally thousands of different menu items at fast food restaurants and dining establishments. The use of this ingredient is widespread and it’s part of the reason we’re seeing skyrocketing rates of cancer in every society that consumes large quantities of processed meats.

So, look for labels on meats that say nitrate-free or nitrate free. You can also cook your own turkey or chicken to make your own lunch meats. When it is made with your hands, you can know for sure that it’s free of this harmful additive.

International Conference on Biomarkers

Conferenceseries LLC invites all the participants from all over the world to attend ‘International Conference on Cancer Biomarkers August 07-09, 2017 Osaka, Japan with the main theme “Innovation and Implementation: Cancer Treatment” which includes prompt keynote presentations, Oral talks, Poster presentations and Exhibitions.

Biomarkers Congress 2017, in the hands of clinical investigators, provide a dynamic and powerful approach to understanding the spectrum of diseases with obvious applications in analytic epidemiology, biomarkers and clinical research in disease prevention, diagnosis, and disease management. Cancer biomarkers have the additional potential to identify individuals susceptible to disease. There is a good scope to know more in this Biomarker Congress In the recent years, the information about cancer biomarkers has increased largely providing great scope for improving the management of cancer patients by improving the accuracy of detection and efficacy of treatment. Latest technological advancement has enabled the examination of many possible biomarkers and renewed interest in developing new biomarkers. All such developments can be evidenced in this Cancer biomarker conference.

Conference Series LLC, the host of this conference is comprised of 3000+ Global Events with over 600+ Conferences, 1200+ Symposiums and 1200+Workshops on diverse Medical, Pharmaceutical, Clinical, Engineering, Science, Technology, Business and Management field is organizing conferences all over the globe. Conferenceseries LLC hosts numerous Molecular Biomarkers, Cancer Biomarkers, Clinical Biomarkers, Cancer Conferences, Cancer meeting , global cancer conference, European Oncology Conferences, Surgical oncology like skin cancer conference, breast cancer conference, liver cancer conference, lung cancer meetings, and Oncology Conferences where knowledge transfer takes place through debates, round table discussions, poster presentations, workshops, symposia and exhibitions and which helps get possibilities for treating the diseases with new era, technology and research.

Track 1: Molecular Biomarkers Discovery:
Disease inquire about systems utilizing mass spectrometry can be utilized to find and approve biomarkers that can be utilized for early discovery of tumor, proteomics in malignancy prognostics, proteogenomics and checking reaction to treatment. They are two sorts of protein test stages are as of now connected to find protein biomarkers and to gauge them quantitatively and subjectively i.e., to decide the isoform condition of a protein, for example, phosphorylation. It is enlightening to bring up here that a counter acting agent utilize is a ‘fit-for-reason’ immune response. For instance, the prerequisite for an ELISA is significantly not the same as that of IHC or indicative measure versus research center test.
Biomarkers are mostly ordered into Protein biomarkers, nucleic corrosive based biomarkers, Lipid biomarkers and Small particle biomarkers. Practically every pharmaceutical organization has been creating sub molecular biomarker programs. There has been a quick increment in the quantity of molecular biomarkers utilized as a part of medication conveyance in the course of the most recent decade.

Track 2: Translational Biomarkers:
Translational Biomarker is the biomarkers that can be applied in both a preclinical and clinical setting. Biomarkers are a measure of a typical natural process in the body, a neurotic procedure, or the reaction of the body to a treatment and may offer data about the component of activity of the medication, its viability, its wellbeing and its metabolic profile. The field of oncology is driving the route in the utilization of biomarkers in medication advancement.
Cancer biomarkers can be classified into Nucleic acid based biomarkers, Pathological biomarkers, Insilico biomarkers, Imaging biomarkers and Glycoprotein biomarkers based on their structure and functioning. All these topics are discussed in these cancer biomarker conferences.

Track 3: Biomarkers: Validation and Verification:
As a result of ordinary clinical or natural fluctuation, competitor biomarkers recognized in the revelation organize should be approved over an expansive number of tests. The test is to build up a quick, focused on examination strategy equipped for breaking down however many recognized hopefuls as could be expected under the circumstances in insignificantly hundreds and conceivably even a huge number of tests. A biomarker competitor confirmation stage wipes out this bottleneck by guaranteeing that lone the most encouraging putative biomarkers found in disclosure go ahead to the approval arrange. To address this test, focused on proteomicswork processes including MRM (Multiple Reaction Monitoring) and SISCAPA (Stable Isotope Standard with Capture by Anti-Peptide Antibodies) are utilized.

Track 4: Clinical biomarkers:
Biomarkers which are utilized for clinical reasons for existing are called clinical biomarkers. Clinical biomarkersalongside Pathological biomarkers give a dynamic and persuasive procedure to comprehension the scope of numerous maladies with utilizations in judgemental and diagnostic the study of disease transmission, subjective clinical trials, screening for medications or illness finding and forecast. Characterized as changes in the constituents of cells or body liquids in these clinical studies. Biomarkers offer the methods for institutionalized arrangement of an ailment and hazard elements, and the can broaden the base data about the fundamental pathogenesis of illness.
The fundamental investigates in clinical biomarkers are done in the fields of medication disclosure, oncology, pharmacogenomics and ailment diagnostics. This biomarker meeting goes in insight about these fields.

Track 5: Biomarkers: Cancers:
Biomarkers play a significant role in cancer prognosis, diagnosis and treatment of cancers these days. There are many types of cancers which are hard to even diagnose. The latest designed biomarkers and their applications provide a great advantage in these cases. Cancer Epidemiology, treatment and latest research is greatly relayed on the biomarkers.
The major types of cancers in which biomarkers are widely being used are breast cancer, lung cancer, prostate cancer and blood cancer. Cancer biomarkers conferences provide a good platform for elaborated discussion on various new researches.

Track 6: Biomarkers and Diseases:
Cardiovascular Disease biomarker is to improve the capacity of the clinician to ideally deal with the patient. For example, in a man with endless or atypical mid-section torment, a biomarker might be required to encourage the recognizable proof of patients with mid-section agony of an ischemic etiology (angina). In a patient exhibiting to the crisis office with intense serious mid-section torment (suspected intense coronary disorder), a biomarker may separate patients with an intense myocardial dead tissue from those with precarious angina, intense pneumonic embolism, or an aortic dismemberment in an opportune manner to encourage focused on administration. In a patient with a set up intense MI, a biomarker might have the capacity to survey the probability of the accompanying: a remedial reaction.

Track 7: Cell free biomarkers:
Without cell or flowing tumor DNA (CtDNA) is tumor DNA circling uninhibitedly in the blood of a malignancy tolerant. Examination of the part of mutant-alleles from CtDNA contrasted with typical alleles from the patient’s ordinary genome gives chances to insignificantly obtrusive growth determination, visualization and tumor observing.
CtDNA begins from biting the dust tumor cells and can be available in an extensive variety of malignancies yet at different levels and mutant allele portions. The CtDNA is exceedingly divided to around 170 bp and is cleared quickly after surgery to evacuate tumors or chemotherapeutic treatment.

Track 8: Predictive Cancer Biomarkers:
There is an impending and squeezing requirement for the recognizable proof of novel circling biomarkers to expand malady free survival rate. So as to encourage the determination of the most encouraging coursing protein biomarkers, we endeavoured to characterize a target technique liable to significantly affect the investigation of inconceivable information created from front line advances. Current study misuses information accessible in seven freely open quality and protein databases.
Another utilization of biomarkers in malignancy pharmaceutical is for sickness visualization, which happens after an individual has been determined to have disease. Here biomarkers can be helpful in deciding the forcefulness of a distinguished disease and in addition its probability of reacting to a given treatment. To some extent, this is on account of tumors displaying specific biomarkers might be receptive to medicines fixing to that biomarker’s demeanor or nearness. Cases of such prognostic biomarkers incorporate raised levels of metallopeptidase inhibitor 1, a marker connected with more forceful types of different myeloma, hoisted estrogen receptor (ER) or potentially progesterone receptorexpression, markers connected with better general survival in patients with bosom cancerHER2/neu quality intensification, a marker showing a breast growth will probably react to trastuzumab treatment a change in exon 11 of the proto-oncogene c-KIT, a marker demonstrating a gastrointestinal stromal tumor (GIST) will probably react to imatinib treatment and transformations in the tyrosine kinase area of EGFR1, a marker showing a patient’s non-little cell lung carcinoma (NSCLC) will probably react to gefitinib or erlotinib treatment.

Track 9: Advances of Biomarker Testing:
Growth biomarkers can likewise be helpful in building up a particular finding. This is especially the situation when there is a need to figure out if tumors are of essential or metastatic inception. To make this refinement, scientists can screen the chromosomal modifications found on cells situated in the essential tumor site against those found in the optional site. On the off chance that the modifications coordinate, the auxiliary tumor can be distinguished as metastatic; while if the changes contrast, the optional tumor can be recognized as a particular essential tumor.
Track 10: Biomarker and Personalized Medicine:
Biomarker testing is a gathering of tests that searches for the sub-atomic indications of wellbeing with the goal that specialists can arrange the best care. Biomarker testing can likewise be called as hereditary testing or sub-atomic testing. Atomic biomarkers, an establishment of exactness oncology, are critical in administration of bosom disease, gastro oesophageal tumor and non-little cell lung malignancy. Testing practices are strongly pondered, impacting symptomatic quality and influencing pathologists, oncologists and patients.
The advances in biomarker testing are fundamentally in the fields of hereditary testing, tumors and different ailments in their determination, treatment and imaging. In silico biomarkers, microRNA biomarkers and a few other clinical biomarkers advanced in the late looks into have opened up the way for biomarker.

Track 11: Companion Diagnostics:
Since tumor markers can be utilized to survey the reaction of a tumor to treatment and for anticipation, analysts have trusted that they may likewise be helpful in screening tests that plan to recognize growth right on time, before there are any side effects. For a screening test to be valuable, it ought to have high affectability and specificity. On the off chance that a test is exceedingly delicate, it will recognize a great many people with the illness that is, it will bring about not very many false-pessimistic results. On the off chance that a test is profoundly particular, just a little number of individuals will test positive for the infection who don’t have it at the end of the day, it will bring about not very many false-positive results. In spite of the fact that tumor markers are greatly valuable in figuring out if a tumor is reacting to treatment or evaluating whether it has repeated, no tumor marker distinguished to date is adequately delicate or particular to be utilized all alone to screen for growth.

Track 12: Biomarkers and Pharmacology:
Biomarkers are exceptionally helpful in the realm of introduction evaluation when managing direct estimation strategies. The utilization of biomarkers in presentation studies is additionally alluded to as biomonitoring. They are chemicals, metabolites, defenselessness attributes, or changes in the body that identify with the presentation of a living being to a synthetic. Biomarkers can distinguish if an introduction has happened the course of presentation, the pathway of introduction, or the subsequent impacts of the introduction.

Track 13: Molecular Imaging and Dynamics:
Molecular Imaging is a cross-teach which a convergence of in vivo imaging is and sub molecular level. It encourages the envisioning of the cell work and the supplement of the sub-atomic process in natural procedures without exasperating the living beings. The different fields of study the Molecular Imaging brings life into are finding of maladies, for example, malignancy, cardiovascular illnesses and neurological issue. This system likewise gives to the impromptu creation of the treatment of different illnesses and clutters by changing the pre-clinical and clinical trial of new medications. The molecular flow gatherings are additionally anticipated that would have a noteworthy monetary effect because of extremely earlier and more exact finding.
Sub-atomic imaging systems utilizing biomarkers prevalently known as Imaging biomarkers have a critical part in screening in different infections especially growth screening utilizing different new era devices and advances. There is an uncommon section for Clinical imaging and Biomarkers in the Molecular imaging.

Track 14: Case reports:
A case report is a point by point report of the side effects, signs, finding, treatment, and follow-up of an individual patient. Case reports may contain a demographic profile of the patient, yet for the most part depict a novel event. Some case reports likewise contain a writing survey of other reported cases related to the different biomarkers. Oncology and malignancy case reports allude to the investigation of the science of growth and tumors at the sub molecular scale. Oncology relies on upon indicative devices like biopsy or expulsion of bits of the tumor tissue and endoscopy for the gastrointestinal tract, imaging concentrates on like X-beams, CT filtering, MRI checking, ultrasound and other radiological methods, Scintigraphy.

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